Buy Benzodiazepines but Ensure Effective and Safe Use!

30 Responses

  1. Alprazolam(Benzodiazepine) says:

    Benzodiazepine is a group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
    Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease.

  2. Molecular Formula: C9H8N2 says:

    Eduardo Costa Figueiredo, Regina Sparrapan, Gustavo Braga Sanvido, Mariane Gonçalves Santos, Marco Aurélio Zezzi Arruda and Marcos Nogueira Eberlin. Quantitation of drugs via molecularly imprinted polymer solid phase extraction and electrospray ionization mass spectrometry: benzodiazepines in human plasma, Analyst, 2011, 136, 3753.

  3. remarkably safe says:

    Side effects
    Benzodiazepines are remarkably safe, especially compared to most other sedatives and tranquilizers. They can be used by people with most medical illnesses and in combination with most other medications. An overdose of benzodiazepines is almost never lethal. They depress breathing very little, creating a problem only for some patients with pulmonary disease. They have little effect on normal sleep patterns, although they may reduce deep sleep a little. Because they may carry some risk of birth defects, physicians are cautious about prescribing them for pregnant women.

    The most common side effect is daytime grogginess or drowsiness, mainly with longer-acting drugs. Short-acting drugs may cause rebound insomnia the night after they are used. At higher doses, benzodiazepines may affect physical coordination and balance, raising the risk of falls and other accidents. Some benzodiazepines can impair memory or the ability to learn and retain new information. Older people are more sensitive to all these side effects.

    The danger of accidents and falls may have been exaggerated. In a recent study, nursing home residents who took benzodiazepines for insomnia had a greater risk of falling than those without insomnia — but were less likely to fall than insomniac patients taking no drugs, who may have been waking up in the night and walking around in the dark.

    Alcohol intensifies almost all benzodiazepine side effects, so physi-cians usually recommend that patients taking benzodiazepines avoid drinking or at least minimize their alcohol consumption.

    Some benzodiazepines are metabolized by the same liver enzyme systems that break down the antibiotic erythromycin, protease inhibitors used to treat HIV infection, and calcium-channel blockers used to treat high blood pressure. When the benzodiazepine is used along with one of these drugs, its effect may last longer than usual.

  4. What is Xanax? says:

    Xanax (alprazolam) is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), flurazepam (Dalmane), and others.

    Xanax works by decreasing abnormal excitement in the brain and was approved by the FDA in October 1981.

    Benzodiazepines act on the brain and central nervous system to produce a calming effect.

    Xanax slows down the movement of brain chemicals that may have become unbalanced, resulting in a reduction in nervous tension and anxiety. Xanax works by boosting the effects of a natural chemical made in the brain called gamma-aminobutyric acid (GABA).

  5. Warnings For all users of Xanax: says:

    To ensure safe and effective use of benzodiazepines, all patients prescribed with Xanax will be provided with the following guidance:

    Inform your doctor about any alcohol consumption and medicine you are currently taking, including over-the-counter (OTC) medication. Alcohol should generally not be used during treatment with benzodiazepines.
    Xanax is not recommended for use in pregnancy. Inform your doctor if you are pregnant, if you are planning to have a child, or if you become pregnant while you are taking this medication.
    Inform your doctor if you are breast-feeding.
    Until you experience how Xanax affects you, do not drive a car or operate heavy or dangerous machinery.
    Do not increase the dose of Xanax without speaking with a doctor, even if you think the medication “does not work anymore.” Benzodiazepines, even when used as recommended, may produce emotional and physical dependence.
    Do not stop taking Xanax abruptly or decrease the dose without consulting your doctor because withdrawal symptoms can occur.

  6. Allergies says:

    Do not use Xanax if you are allergic to alprazolam or other benzodiazepines such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

  7. Alcohol says:

    Do not drink alcohol while taking Xanax. Xanax can increase the effects of alcohol.

  8. Pregnancy says:

    Do not use Xanax if you are pregnant. Benzodiazepines can potentially cause harm to the fetus. Xanax increases the risk of congenital abnormalities when given to a pregnant woman during the first trimester.

  9. Use of Xanax during the first trimester of pregnancy should usually be avoided. says:

    paxub@kumail8.info

  10. Nursing says:

    It is thought that Xanax is excreted in human milk. As a general rule, mothers who must use Xanax should not breast-feed.

  11. Older adults says:

    Older adults may be more sensitive to the effects of benzodiazepines. The sedative effects of Xanax may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Xanax.

  12. Smoking says:

    Xanax concentrations may be reduced up to 50 percent in smokers, compared with nonsmokers.

  13. Abuse says:

    Xanax is often abused for the fast-acting, relaxed “high” it can give to people who take it, including people without a prescription.

    According to the Treatment Episode Data Set, the number of individuals seeking treatment for benzodiazepine abuse almost tripled from 1998-2008. Long-term abuse and addiction to Xanax are associated with depression, psychotic experiences, and aggressive or impulsive behavior.

    According to the Substance Abuse and Mental Health Services Administration, in 2011, there were over 1.2 million emergency department (ER) visits overall related to the nonmedical use of prescription drugs – Xanax was involved in 10 percent of those visits.

    The number of emergency department visits involving the non-medical use of the sedative Xanax doubled from 57,419 to 124,902 during the years 2005 to 2010 and then remained stable at 123,744 in 2011.

    The most common drug combinations encountered in ER patients are Xanax and alcohol, and Xanax combined with prescription opiates like hydrocodone and oxycodone.

  14. Uses says:

    Xanax is used to manage anxiety disorder or the short-term relief of symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment.

    Generalized anxiety disorder is characterized by unrealistic or excessive anxiety and worry about two or more life circumstances, for a period of 6 months or longer, during which the person has been bothered more days than not by these concerns.

    At least six of the following symptoms are often present in these patients:

    Motor tension: trembling, twitching, feeling shaky, muscle tension, aches or soreness, restlessness, easily tired.
    Autonomic hyperactivity: shortness of breath or smothering sensations, palpitations or accelerated heart rate, sweating, or cold, clammy hands, dry mouth, dizziness or light-headedness, nausea, diarrhea, or other abdominal distress, flushes or chills, frequent urination, trouble swallowing or a “lump in the throat.”
    Vigilance and scanning: feeling keyed up or on edge, exaggerated startle response, difficulty concentrating or “mind going blank” because of anxiety, trouble falling or staying asleep, irritability.
    Xanax is also indicated for the treatment of panic disorder, with or without agoraphobia, and may reduce the number of panic attacks experienced.

    Panic disorder is characterized by regular panic attacks. Panic attacks are relatively short periods of intense fear or discomfort where four or more of the following symptoms develop all of a sudden and reach a peak within 10 minutes:

    Palpitations, pounding heart, or accelerated heart rate.
    Sweating.
    Trembling or shaking.
    Sensations of shortness of breath or smothering.
    Feeling of choking.
    Chest pain or discomfort.
    Nausea or abdominal distress.
    Feeling dizzy, unsteady, lightheaded, or faint.
    Derealization (feelings of unreality) or depersonalization (being detached from oneself).
    Fear of losing control.
    Fear of dying.
    Paresthesia (numbness or tingling sensations).
    Chills or hot flushes.

  15. What is lorazepam? says:

    Lorazepam belongs to a group of drugs called benzodiazepines. It affects chemicals in the brain that may be unbalanced in people with anxiety.

    Lorazepam is used to treat anxiety disorders.

    Lorazepam may also be used for purposes not listed in this medication guide

  16. Important information says:

    You should not use lorazepam if you have narrow-angle glaucoma or myasthenia gravis, or if you are allergic to Valium or a similar medicine.

    Do not use lorazepam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn.

    Lorazepam may be habit-forming and should be used only by the person it was prescribed for. Misuse of habit-forming medicine can cause addiction, overdose, or death. Lorazepam should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

    Do not drink alcohol while taking lorazepam. This medication can increase the effects of alcohol.

  17. Before taking this medicine says:

    It is dangerous to purchase lorazepam on the Internet or from vendors outside the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. The sale and distribution of lorazepam outside the U.S. does not comply with the regulations of the Food and Drug Administration (FDA) for the safe use of this medication.

    You should not take lorazepam if you have:

    narrow-angle glaucoma;

    myasthenia gravis; or

    a history of allergic reaction to any benzodiazepine, such as diazepam (Valium), chlordiazepoxide, clonazepam, flurazepam, and others.

    To make sure lorazepam is safe for you, tell your doctor if you have:

    seizures or epilepsy;

    kidney or liver disease (especially alcoholic liver disease);

    asthma or other breathing disorder;

    open-angle glaucoma;

    a history of depression or suicidal thoughts or behavior;

    a history of drug or alcohol addiction; or

    if you use a narcotic (opioid) medication.

  18. Do not use lorazepam if you are pregnant. says:

    This medicine can cause birth defects. Your baby could also become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are taking lorazepam.

    Lorazepam can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

  19. How should I take lorazepam? says:

    Take lorazepam exactly as it was prescribed for you. Follow all directions on your prescription label. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

    Lorazepam may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

  20. What happens if I miss a dose? says:

    Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose

  21. Lorazepam side effects says:

    Get emergency medical help if you have signs of an allergic reaction to lorazepam: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Call your doctor at once if you have:

    severe drowsiness;

    thoughts of suicide or hurting yourself;

    unusual changes in mood or behavior;

    confusion, aggression, hallucinations;

    worsened sleep problems;

    sudden restless feeling or excitement;

    muscle weakness, drooping eyelids, trouble swallowing;

    vision changes; or

    upper stomach pain, dark urine, jaundice (yellowing of the skin or eyes).

  22. Lorazepam dosing information says:

    Usual Adult Dose of Lorazepam for Anxiety:

    Tablets:
    Initial dose: 2 to 3 mg orally per day administered 2 to 3 times per day
    Maintenance dose: 1 to 2 mg orally 2 to 3 times a day
    Parenteral:
    IV: 2 mg total, or 0.044 mg/kg, whichever is smaller

    Comments:
    -The daily dosage may vary from 1 to 10 mg per day.
    -The dosage should be increased gradually when needed to help avoid adverse effects.
    -When higher dosage is indicated, the evening dose should be increased before the daytime doses.

    Use: Management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

    Usual Adult Dose for Light Anesthesia:

    IM: 0.05 mg/kg up to a maximum of 4 mg
    IV: 2 mg total, or 0.044 mg/kg, whichever is smaller

    Comments:
    -Doses of other injectable central-nervous-system depressant drugs should be reduced.
    -For optimum effect, intramuscular drug should be administered at least 2 hours before the anticipated operative procedure.
    -Narcotic analgesics should be administered at their usual preoperative time.
    -IV: This dose should not ordinarily be exceeded in patients over 50 years of age.
    -IV: Larger doses as high as 0.05 mg/kg up to a total of 4 mg may be administered.
    -For optimum effect, intravenous drug should be administered 15 to 20 minutes before the anticipated operative procedure.

    Use:
    -Preanesthetic medication for adult patients, producing sedation (sleepiness or drowsiness), relief of anxiety, and a decreased ability to recall events related to the day of surgery

  23. Usual Adult Dose for Status Epilepticus: says:

    0.1 mg/kg IV up to 4 mg per dose; may repeat in 5 to 10 minutes
    Maximum dose: 8 mg

    Comments:
    -Vital signs should be monitored, an unobstructed airway should be maintained, and artificial ventilation equipment should be available.
    -When an intravenous port is not available, the IM route may prove useful.

    Use: Treatment of status epilepticus

    Usual Adult Dose for Insomnia:

    2 to 4 mg orally administered at bedtime

    Comments:
    -The dosage should be increased gradually when needed to help avoid adverse effects.

    Use: Management of insomnia

  24. Usual Pediatric Dose for Anxiety: says:

    12 years or older:
    Initial dose: 2 to 3 mg orally per day administered 2 to 3 times per day
    Maintenance dose: 1 to 2 mg orally 2 to 3 times a day

    Comments:
    -The daily dosage may vary from 1 to 10 mg per day.
    -The dosage should be increased gradually when needed to help avoid adverse effects.
    -When higher dosage is indicated, the evening dose should be increased before the daytime doses.

    Use: Management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

  25. What other drugs will affect lorazepam? says:

    Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking lorazepam with a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression or seizures.

    Tell your doctor about all your current medicines and any you start or stop using, especially:

    any other medicines to treat anxiety;

    probenecid;

    aminophylline or theophylline;

    an antidepressant, or medicine to treat mental illness;

    a barbiturate such as phenobarbital;

    narcotic pain medicine;

    seizure medicine; or

    medicine that contains an antihistamine (such as sleep medicine, cold or allergy medicine).

    This list is not complete. Other drugs may interact with lorazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

  26. Which medications are safe and effective for improving sleep at high altitude? says:

    Given the well-established problems with sleep at high altitude, it is not uncommon for people planning trips to the mountains to seek advice from clinicians regarding pharmacologic options for improving sleep during their trip. This review article considers the various medications that have been studied for this purpose at high altitude with an emphasis on both their efficacy and safety. The available data support the use of either acetazolamide, temazepam, zolpidem or zaleplon in this environment. Other agents commonly used at sea-level such as eszopiclone and diphenhydramine have not been studied at high altitude but are likely safe to use given their mechanism of action and known side effects. Limited evidence suggests diazepam may cause hypoventilation at high altitude and its use in this environment should be discouraged. Insufficient data exist to determine which agent is most effective at altitude nor do we know whether combination therapy with acetazolamide and a hypnotic agent offers any benefits over monotherapy.

  27. Mental Health Medications says:

    Medications can play a role in treating several mental disorders and conditions. Treatment may also include psychotherapy (also called “talk therapy”) and brain stimulation therapies (less common). In some cases, psychotherapy alone may be the best treatment option. Choosing the right treatment plan should be based on a person’s individual needs and medical situation, and under a mental health professional’s care.

    The National Institute of Mental Health (NIMH), a Federal research agency, does not provide medical advice or referrals. Resources that may help you find treatment services in your area are listed on our Help for Mental Illnesses web page.

    NIMH also does not endorse or recommend any particular drug, herb, or supplement. Results from NIMH-supported clinical research trials (What are Clinical Research Trials?) that examine the effectiveness of treatments, including medications, are reported in the medical literature. This health topic webpage is intended to provide basic information about mental health medications. It is not a complete source for all medications available and should not be used as a guide for making medical decisions.

    Information about medications changes frequently. Check the U.S. Food and Drug Administration (FDA) website for the latest warnings, patient medication guides, or newly approved medications. Brand names are not referenced on this page, but you can search by brand name on MedlinePlus Drugs, Herbs and Supplements Drugs website. The MedlinePlus website also provides additional information about each medication, including side effects and FDA warnings.

  28. Understanding Your Medications says:

    If you are prescribed a medication, be sure that you:

    Tell the doctor about all medications and vitamin supplements you are already taking.
    Remind your doctor about any allergies and any problems you have had with medicines.
    Understand how to take the medicine before you start using it and take your medicine as instructed.
    Don’t take medicines prescribed for another person or give yours to someone else.
    Call your doctor right away if you have any problems with your medicine or if you are worried that it might be doing more harm than good. Your doctor may be able to adjust the dose or change your prescription to a different one that may work better for you.
    Report serious side effects to the FDA MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088]. You or your doctor may send a report.

  29. What are antidepressants? says:

    Antidepressants are medications commonly used to treat depression. Antidepressants are also used for other health conditions, such as anxiety, pain and insomnia. Although antidepressants are not FDA-approved specifically to treat ADHD, antidepressants are sometimes used to treat ADHD in adults.

    The most popular types of antidepressants are called selective serotonin reuptake inhibitors (SSRIs). Examples of SSRIs include:

    Fluoxetine
    Citalopram
    Sertraline
    Paroxetine
    Escitalopram
    Other types of antidepressants are serotonin and norepinephrine reuptake inhibitors (SNRIs). SNRIs are similar to SSRIs and include venlafaxine and duloxetine.

    Another antidepressant that is commonly used is bupropion. Bupropion is a third type of antidepressant which works differently than either SSRIs or SNRIs. Bupropion is also used to treat seasonal affective disorder and to help people stop smoking.

    SSRIs, SNRIs, and bupropion are popular because they do not cause as many side effects as older classes of antidepressants, and seem to help a broader group of depressive and anxiety disorders. Older antidepressant medications include tricyclics, tetracyclics, and monoamine oxidase inhibitors (MAOIs). For some people, tricyclics, tetracyclics, or MAOIs may be the best medications.

  30. How do people respond to antidepressants? says:

    According to a research review by the Agency for Healthcare Research and Quality, all antidepressant medications work about as well as each other to improve symptoms of depression and to keep depression symptoms from coming back. For reasons not yet well understood, some people respond better to some antidepressant medications than to others.

    Therefore, it is important to know that some people may not feel better with the first medicine they try and may need to try several medicines to find the one that works for them. Others may find that a medicine helped for a while, but their symptoms came back. It is important to carefully follow your doctor’s directions for taking your medicine at an adequate dose and over an extended period of time (often 4 to 6 weeks) for it to work.

    Once a person begins taking antidepressants, it is important to not stop taking them without the help of a doctor. Sometimes people taking antidepressants feel better and stop taking the medication too soon, and the depression may return. When it is time to stop the medication, the doctor will help the person slowly and safely decrease the dose. It’s important to give the body time to adjust to the change. People don’t get addicted (or “hooked”) on these medications, but stopping them abruptly may also cause withdrawal symptoms

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