Buy Cannabinoids as Advised by Health Practitioners

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  1. Medical cannabis says:

    Abstract
    Cannabis has been widely used as a medicinal agent in Eastern medicine with earliest evidence in ancient Chinese practice dating back to 2700 BC. Over time, the use of medical cannabis has been increasingly adopted by Western medicine and is thus a rapidly emerging field that all pain physicians need to be aware of. Several randomized controlled trials have shown a significant and dose-dependent relationship between neuropathic pain relief and tetrahydrocannabinol – the principal psychoactive component of cannabis. Despite this, barriers exist to use from both the patient perspective (cost, addiction, social stigma, lack of understanding regarding safe administration) and the physician perspective (credibility, criminality, clinical evidence, patient addiction, and policy from the governing medical colleges). This review addresses these barriers and draws attention to key concerns in the Canadian medical system, providing updated treatment approaches to help clinicians work with their patients in achieving adequate pain control, reduced narcotic medication use, and enhanced quality of life. This review also includes case studies demonstrating the use of medical marijuana by patients with neuropathic low-back pain, neuropathic pain in fibromyalgia, and neuropathic pain in multiple sclerosis. While significant preclinical data have demonstrated the potential therapeutic benefits of cannabis for treating pain in osteoarthritis, rheumatoid arthritis, fibromyalgia, and cancer, further studies are needed with randomized controlled trials and larger study populations to identify the specific strains and concentrations that will work best with selected cohorts.

    Keywords: randomized controlled trials, tetrahydrocannabinol, addiction, social stigma, fibromyalgia, neuropathic pain
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    Medical cannabis in history and society
    Cannabis sativa (cannabis) has been used therapeutically for almost 5,000 years, beginning in traditional Eastern medicine.1 Some of the earliest evidence for this is found in the pen-ts’ao ching, the world’s first pharmacopeia, compiled based on ancient Chinese practices from as early as 2700 BC.1 It was not until 1841 that medical cannabis was introduced into Western medicine through the work of William O’Shaughnessy, an Irish physician, who encountered “Indian hemp” in Calcutta. By the late 19th century, medical cannabis became widely disseminated in the Americas; cannabis-based extracts, tinctures, cigarettes, and plasters produced by early prominent drug companies2,3 were indicated for a wide range of conditions, many of which were related to pain.1,4 Even Sir William Osler, the preeminent Canadian internist, wrote in The Principles and Practice of Medicine (1892) that “Cannabis Indica is probably the most satisfactory remedy for migraines”. However, the medical use of cannabis fell from favor in the 1930s and 1940s when fear escalated that recreational use of cannabis may be related to violence, crime, and other socially deviant behaviors. At that time, widespread prohibitive legislation banning the use of cannabis-based medicines occurred across the world.2 More recently, the medical use of cannabis has been reintroduced in a number of countries for the treatment of a variety of conditions, including pain.5,6

    Indeed, support for medical cannabis appears to be on the rise. Overwhelmingly, patients prescribed medical cannabis for pain-related illnesses report being highly successful with pain reduction as well as with reducing their use of other medications. In a recent large survey of medical cannabis users in Arizona, 77% of fibromyalgia patients, 63% of patients with arthritis, and 51% of patients suffering from neuropathic pain reported experiencing “a lot or almost complete overall pain relief ”.7 Most patients with these conditions (94% of patients with fibromyalgia, 81% of arthritic patients, and 61% of patients with neuropathy) also found that they were able to lower their use of their other medications such as narcotic opioids.7 In fact, 75% of opioid-dependent medical cannabis users reported experiencing “a lot or almost complete overall relief ” from opioid dependency.7 Studies such as this shed light onto the wide range of clinical uses of medical cannabis, making it highly useful, since evidence from controlled clinical trials is still emerging.

    Studies examining the characteristics of medical cannabis patients in the US have revealed that the majority medicate daily7–9 and consume 6–9 g of cannabis per week.8 In Canada, 42% of medical cannabis patients reported medicating two to three times per day, and 40% consume >14 g per week.10 In both Canada and the US, most patients choose inhalation as their preferred method of consumption.7,10

    In addition to patients with access to prescribed medical cannabis, there is also a huge population of users who consume cannabis recreationally or for self-defined medical reasons. Cannabis is the most commonly used illicit drug in the world,11 with 7% of adults in the US reporting use within the last 30 days and 34% reporting having used in 2015.12 Interestingly, only 53% of adult cannabis users in the US consume cannabis exclusively for recreational purposes, while the other 47% of users consume cannabis “in part or entirely for medicinal purposes”, with 10% using solely for medicinal purposes.12 In Canada, ~4% of residents over the age of 14 reported at least one instance of past-year cannabis use to treat self-defined medical conditions in 2004.13,14

  2. Healthcare benefits says:

    annabinoids originated from marijuana or hemp seed and has substances that induce both mental and physical effect on humans. Although cannabinoids made up of CBD have healthcare benefits which help to reduce anxiety, cannabinoids that contain THC and/or tetrahydrocannabinol can stimulate hallucinations and anxiousness. Cigarette smoking or esmoking cannabinoids with THC is equivalent to smoking cannabis because it has the same euphoric effects.

    Farming of cannabis or hemp seed is acceptable in many parts of the world these days because it has several uses in industries such as fabrics, food digesting, vehicle, paper and the like. Even though there tend to be more than eighty different strains associated with cannabinoids which are found in the medical cannabis plant, one of the most common are CBD and THC that have totally varied features because the former has medicinal advantages while the second item features psychoactive properties.

    Common Effect of Cannabinoids
    In accordance with the latest study regarding cannabinoids, these possess a unique impact on our bodies on a particular part of nerves inside the body known as endocannabinoid system. These studies were done by Raphael Mechoulam Hebrew University in Jerusalem. It exposed new information associated with biochemistry and biology by which brain’s reaction to the usage of various strains of cannabis is being researched. These studies demonstrated that cannabinoids work as modulators with brain’s neurotransmitters as well as trigger biological effect on understanding, urge for food and physical nerves.

    These types of cannabinoid receptors tend to be more than usual receptors of the human body and are found throughout the body when they’re triggered; it results in a number of physiological functions. These types of receptors have been classified into a couple of parts known as CB1, and CB2 involving which the 1st one is located in the human brain and sideline tissue as the 2nd receptor is manifested directly into tissues and vital internal organs. The biggest power of CB2 receptor is located in the spleen accompanied by defense mechanisms and cardiovascular function in overweight.

    Anti-Oxidant Impact of Cannabinoids
    Together CBD plus THC Cannabinoids have aromatic terpenoids that can help cannabinoids to give unique flavor and taste to vaping fluids included in e-cigarettes. The particular neuroprotective anti-oxidants both in THC and CBD protect against oxidative harm and are more defensive as compared to Vitamin E D-alpha or Ascorbic Acid. The particular receptors for cannabinoid tend to be the largest group of receptors within your body and therefore are known as a G-protein-coupled receptor. All the cannabinoids which are nonpsychotropic can easily be made use of for their anti-inflammatory qualities and can help out with modulation of soreness in your body.

  3. Getting Started with Medical Marijuana says:

    Modern research suggests that cannabis is a valuable aid in the treatment of a wide range of clinical applications. These include pain relief — particularly neuropathic pain — nausea, spasticity, glaucoma, and movement disorders. Marijuana is also a powerful appetite stimulant, specifically for patients suffering from HIV, the AIDS wasting syndrome, or dementia. Emerging research suggests that cannabinoids and terpenes found in cannabis work together synergistically to help protect the body against some types of malignant tumors.

    Currently, more than 60 U.S. and international health organizations — including the American Public Health Association, Health Canada and the Federation of American Scientists — support granting patients immediate legal access to medicinal marijuana under a physician’s supervision. Several others, including the American Cancer Society and the American Medical Association support the facilitation of wide-scale, clinical research trials so that physicians may better assess cannabis’ medical potential.

    In addition, a 1991 Harvard study found that 44 percent of oncologists had previously advised marijuana therapy to their patients. Fifty percent responded they would do so if marijuana was legal. A more recent national survey performed by researchers at Providence Rhode Island Hospital found that nearly half of physicians with opinions supported legalizing medical marijuana.

  4. Safety and Efficacy says:

    Cannabis and its psychoactive cannabinoid, THC, are considered incredibly safe for human consumption. The Drug Awareness Warning Network Annual Report, published by the Substance Abuse and Mental Health Services Administration (SAMHSA), contains a statistical compilation of all drug deaths which occur in the United States. According to this report, there has never been a death recorded from the use of cannabis. In fact, many studies show it is physically impossible for a human to die from a cannabis overdose.

    The documented use of cannabis as a safe and effective therapeutic botanical dates to 2700 BC. Between 1840 and 1900, European and American journals of medicine published more than 100 articles on the therapeutic use of cannabis. In fact, cannabis was part of the American pharmacopoeia until 1942, and is currently available by prescription in Canada, the Netherlands, Israel, and Germany.

  5. Therapeutic Benefits says:

    The cannabis plant has been around for centuries. It is believed to have originated in Central Asia, but has expanded its reach to an international scale over time. People all around the globe consume cannabis and their reasoning is largely the same: it makes them feel better.

    We know that humans have cannabinoid receptors housed inside the body that are ready to bind with cannabinoids found in the cannabis plant to provide therapeutic benefits for a variety of ailments. In fact, cannabinoid receptors are present in humans before birth and the compounds themselves are even found in a mother’s breast milk. Medical cannabis gains merit when you consider our bodies are naturally tuned to interact with cannabinoids, and even more so when you acknowledge the growing evidence of benefits to cannabis consumption.

  6. Cannabis & Digestion says:

    t is no secret – experiencing “the munchies” is one of the most obvious cannabis clichés. Despite the silly connotation, studies suggest that the endocannabinoid system actually helps modulate appetite. This is especially interesting for the treatment of eating disorders. In fact, a study published in the International Journal of Eating Disorders suggests that cannabinoids may prove effective in treating anorexia.

    Cannabis is also famously used to reduce the feelings of nausea but studies suggest it could have a number of digestive benefits as well. Medical marijuana could play a role in a number of digestion-related health conditions including:

    Crohn’s Disease and Cannabis
    Obesity and Cannabis
    Diabetes and Cannabis

  7. Medical Marijuana For Pain Management says:

    Chronic Pain is one of the most common ailments for which doctors prescribe medical marijuana and a recent survey published in The Spine Journal found that 1 out of 5 patients at a Colorado spine center were using cannabis to manage their pain. Of those, nearly 90% said it greatly or moderately relieved their pain.

    The spine clinic study was merely a survey, which means more research will be necessary on the potential role of cannabis in treating back pain. With that said, plenty of people will tell you it helps manage pain and science is beginning to back their claims. Studies suggest medical marijuana could offer relief for various types of pain, including the following:

    Chronic Pain and Cannabis
    Neuropathic Pain and Cannabis

  8. Cannabis & Mental Health says:

    A common misconception of cannabis is that has detrimental effects on mental health. It is possible that high doses of tetrahydrocannabinol (THC) could trigger anxiety in some patients, and some believe it could expedite the onset of predisposed personality disorders, but this has yet to be proven by any reputable studies.

    The recent trend in the mental health field has been to investigate our relationship with cannabis. In turn, studies have linked cannabinoids to a number of mental health concerns. The research catalog is still growing, but a few mental health conditions for which cannabis could be beneficial are as follows:

    Alcoholism and Cannabis
    Opiate Withdrawal and Cannabis
    Depression and Cannabis
    Phobias and Cannabis
    Schizophrenia and Cannabis

  9. Your Brain On Cannabis says:

    Not only has cannabis been linked to mental health, cannabinoid receptor activity in the brain before birth suggests that the compounds could be play a role in brain development. Cannabis has been linked to the creation of new neurons in the brain, or neurogenesis, and overall brain plasticity. In addition to its role in brain development, medical cannabis is believed to have neuroprotective properties that help treat the following conditions:

    Alzheimer’s Disease and Cannabis
    Parkinson’s Disease and Cannabis
    Oxygen Deficits and Cannabis
    Migraines and Cannabis

  10. Medical Marijuana For Cancer says:

    One the most intriguing potential applications for medical marijuana is cancer treatment. It has long been prescribed to counter the side effects of chemotherapy, but oncologists across the world are working on trials to determine whether cannabis can be used to treat cancer itself. Many patients choose to take the Rick Simpson Oil treatment plan in an attempt to cure the cancer, but there are many different methods of going about treatment.

    Past research showed promise for THC in cancer treatment, but many are skeptical of using THC-based products because of its psychotropic effects (eg. the “high”). As a result many oncologists have redirected their focus toward cannabidiol (CBD) and cannabigerol (CBG). A recent British study, however suggests that cannabinoids may be most effective against cancer when combined in a manner that allows them to act synergistically with one-another. Below is a short list of studies and research supporting cancer treatment with medical cannabis to get you started:

    Breast Cancer and Cannabis
    Brain Cancer and Cannabis
    Lung Cancer and Cannabis
    Skin Cancer and Cannabis
    Tumor Growth and Cannabis

  11. Becoming a Patient says:

    There are just four basic steps to becoming a legal medical marijuana patient in your state:

    Proof of residence
    This is most easily proven with a valid driver’s license.
    Eligible condition
    The list of eligible health conditions for access to medical marijuana varies from state to state. Many conditions, such as cancer, glaucoma, HIV / AIDS, neuropathic pain, arthritis, and other such severe and debilitating or terminal illnesses qualify in most states.
    Knowledge of your local laws
    Medical cannabis patients and their providers are vulnerable to federal and state raids, arrest, prosecution, and incarceration. As a result, these individuals may suffer pervasive discrimination in employment, child custody, housing, public accommodation, education, and medical care. Laws protecting patients and their providers vary from state to state and, in some cases, may vary from county to county.
    Consent from a physician or other qualifying medical professional
    It is best to work with your primary care physician, but if they are reluctant or you don’t have one, you can find a list of doctors familiar with medical cannabis on NORML’s Website.

  12. MDMB-CHMCZCA says:

    DMB-CHMCZCA Cannabinoid from www.highstore.net the E.Us Research Chemical Wholesale Supplier,
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    MDMB-CHMCZCA / Methyl 2-(9-(cyclohexylmethyl)-9H-carbazole-3-carboxamido)-3,3-dimethylbutanoate is the carbazole analogue of MDMB-CHMICA (which everyone calls MMB-CHMINACA) and is a synthetic cannabinoid, and is in the form off an tan powder.

    It is an carbazole based cannabinoid that is the carbazole analogue of MMB-CHMINACA (a.ka MDMB-CHMICA) and so is perfect for researchers in countries where other cannabinoids are controlled. It appears to have in-vitro CB1/CB2 receptor agonism about the same zone as 5F-AKB48.

    PLEASE NOTE – This compound appears to have significantly greater in-vitro binding affinities than many of the current cannabinoids and researchers should take this into account when carefully planning their experiments and the amount of material to deploy onto cellular substrates.

    Laboratory scales are a must in handling this material

  13. MMB-CHMINACA says:

    formally known as (2S)-methyl-2-(1-(cyclohexylmethyl)-1 H-indol-3-ylcarbonylamino)-3,3-dimethylbutanoate, is the very latest new synthetic cannabinoid research chemical.

    PLEASE NOTE – This compound appears to have significantly greater in-vitro binding affinities than many of the current cannabinoids, and researchers should take this into account when carefully planning their experimentation, and the amount of material to deploy onto cellular substrates. Laboratory scales are a must in handling this material, to assist with accurate measuring.

    This is an indole based cannabinoid that shares some structural similarities with AB-CHMINACA, but it has a dimethylbutanoate grouping.

    Scientists can conduct experiments to determine the basic data on the material, such as melting points, and solublities etc. To see how it compares and contrasts with the data from similar chemicals.

    The feedback we are getting indicates that this is one of the best cannabinoids around.

    Please note this as with all of our Cannabnoids is NOT for human consumption.

    Must be over 18 to purchase.

    MMB-CHMINACA CANNABINOID can only be ordered if you are over 18 years of age.

  14. OG KUSH CBD CAKE says:

    When CannaShock released the OG Kush CBD Cake, and it hit the streets of Amsterdam, people couldn’t believe that a product this good, could be legal, but it is!

    You can store these cakes in the fridge, or freeze them and eat later. These CBD cakes will stay super fresh for nearly one year, when frozen. Once defrosted, it should stay fresh for 10 weeks, if kept in it’s packaging and stored in a fridge.

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    OG Kush CBD Cake can only be ordered if you are over 18 years of age.

    Please ensure that OG Kush CBD Cake is NOT controlled in the country/state to which you wish it to be delivered.

    OG Kush CBD Cake is not for human consumption.

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