MMB-CHMINACA – Sold as a Designer Drug Online!
MMB-CHMINACA is also sometimes known as MMB-CHMICA. This is a potential agonist of the so-called CB1 receptor. And, so far, this is sold as a designer drug online. This is somehow identified in the designer drug market being an AMB-CHMINACA.
Pharmacology and Chemistry
MMB-CHMINACA is actually known to function as a potent full agonist of the so-called CB1 receptor. This is also known for its efficacy of about 94%. This has its EC50 value of about 0.14nM. This is approximately eight times lower than the EC50 of the JWH-018. This is also 2-fold lower as compared to the AB-CHMINACA.
There were also already many commercial samples of the MDMB-CHMICA. These were known to contain s-enantiomer based on electronic and vibrational circular dichroism spectroscopy. Actually, the (S)-configuration for the so-called tert-leucinate group is not surprising. This is due to the very reason that the MDMB-CHMICA is synthesized from the inexpensive and abundant “L” form of the tert-leucinate reactant.
Metabolism and Side Effects
MDMB-CHMINACA is known for its metabolic reactions that are consisted of the hydrolis and mono-hydroxylations of the carboxylic ester function. In totality, thirty-one metabolites were able to be identified in vivo.
The side effects include of seventy-one serious adverse events. These include forty-two acute intoxications and twenty-nine deaths. All these occurred in different countries. These also include of hyperemesis, coma or unconsciousness, convulsions, seizures, mydriasis, shortness of breathing, defecating, metabolic acidosis, respiratory acidosis, chest pain, and severe disturbance in the behavior.
MBMB-CHMICA is basically classified as a Schedule I controlled substance in the United States. This is also somehow illegal in the countries like Greece, Finland, Estonia, Denmark, Croatia, Canada, China and Austria. Even the European Commission banned this synthetic cannabinoid in the European Union. They also adopted an implementation that banned this cannabinoid. The Member States also took the necessary measures prior to criminal penalties and control measures.
Now, you have learned more about the MMB-CHMINACA being a designer drug!