Buy Cannabidol and Discover More of Its Medicinal Uses!

37 Responses

  1. Cannabidiol says:

    ore than 100 cannabinoids have been identified within the cannabis plant, that is, chemical compounds found naturally in the plant. One of the most abundant is cannabidiol (CBD), which can represent up to 45% of the plant extract. Many of the Cannabis Sativa strains give rise to CBD or cannabidiol but do so in small amounts. In fact, only certain branches of the plant contain sufficient concentration of CBD to extract it in a useful way.

    The first time that CBD was isolated from the cannabis plant was between 1930 and 1940 by researchers at the University of Illinois (USA). However, it was not until the 1960s when Professor Rafael Mechoulam managed to describe its structure and chemical composition. Since 2013, PubMed, an American medical research database, has indexed more than 1,500 studies on cannabidiol. Because of this, many scientists consider CBD to be one of the most important cannabinoids discovered to date.

  2. Cannabidiol Basics says:

    f you’re new to cannabidiol, you’ll want to start here.

    In this section you’ll discover topics like benefits, current research, legal status, history, and many more.

    What is CBD (Cannabidiol)?
    CBD vs THC: What is the Difference?
    What is Cannabidiol’s Legal Status?
    How Does CBD Work?
    Hemp vs Marijuana: What’s the Difference?
    What’s the Difference Between CBD Oil from Medical Marijuana and CBD Oil from Industrial Hemp Oil?

  3. Latest Cannabidiol News says:

    Our blog showcases the latest news in the ever growing cannabidiol industry. See as CBD oil gets mentioned by Michael Pollan, CNN’s Sanjay Gupta and more!

    To read the latest news on CBD head to our blog here.

  4. What is CBD (Cannabidiol)? says:

    “So what is CBD (Cannabidiol), anyway?” is a question we are commonly asked.

    Cannabidiol, also known as CBD, is a natural substance that has recently come into the spotlight for a number of reasons.

    It is a relatively new food supplement that is still being researched, and while the initial results are promising, there is a lot of doubt, misinformation, and sheer confusion surrounding it.

    Recently, CBD oil has become an accepted means of relaxation, and the substance’s popularity is rising fairly rapidly.

    As the use of CBD oil is very new, there are still significant gaps in what we know about its effects. While we can confidently say the substance is safe and legal, its exact benefits are still an issue of hot debates and fervent research.

    In this article, we are putting the most important facts surrounding Cannabidiol together to cut through some of the confusion and give you a clearer picture about this new cannabinoid known as CBD. This article covers:

    The benefits of CBD
    Where does CBD come from?
    CBD’s legal status (and the confusion surrounding it!)
    Finally, we have included our “Cannabidiol Definitions” section to help you make sense of all the technical terms and jargon surrounding CBD.

  5. What Are the Benefits of CBD? says:

    Numerous people are reporting success in using CBD to reach a desired state of calm and relaxation.

    Strictly as a chemical substance, CBD also has strong antioxidant properties, a fact that so far has been largely ignored by the broader food supplements industry.

    As each person is different, and because CBD’s effects are still under study, we strongly encourage you to do your own research before incorporating CBD to your daily life.

  6. non-psychoactive.1 says:

    This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.


    Formal Name :2-[1R-3-methyl-6R-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
    CAS Number: 13956-29-1
    Synonyms: CBD
    Molecular Formula: C21H30O2
    Formula Weight
    A crystalline solid
    OC(C=C(C=C1O)CCCCC)=C1[[email protected]]2[[email protected]](C(C)=C)CCC(C)=C2
    InChI Code
    InChI Key


    Product Description References
    1. Kozela, E.,Juknat, A.,Kaushansky, N., et al. Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. J.Neuroinflamm. 12(52), (2015).

    2. Mechoulam, R.,Peters, M.,Murillo-Rodriguez, E., et al. Cannabidiol – Recent advances. Chemistry & Biodiversity 4, 1678-1692 (2007).

    3. Pertwee, R.G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: δ9-Tetrahydrocannabinol, cannabidiol and δ9-tetrahydrocannabivarin. Br. J. Pharmacol. 153(2), 199-215 (2008).

    4. Ryberg, E.,Larsson, N.,Sjögren, S., et al. The orphan receptor GPR55 is a novel cannabinoid receptor. British Journal of Pharmacology 152, 1092-1101 (2007).

    5. Russo, E.B.,Burnett, A.,Hall, B., et al. Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochemical Research 30(8), 1037-1043 (2005).

    6. Campos, A.C.,Moreira, F.A.,Gomes, F.V., et al. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Phil.Trans.R.Soc.B. 367, 3364-3378 (2012).

    7. Kathmann, M.,Flau, K.,Redmer, A., et al. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. Naunyn-Schmiedeberg’s Arch.Pharmacol. 372(5), 354-361 (2006).

  9. Anti-inflammatory says:

    A number of studies on CBD indicate that it may be useful in treating inflammation caused by a variety of conditions. A 2012 study published in the European Journal of Pharmacology concluded that cannabidiol has anti-inflammatory effects in a murine model of acute lung injury and that this effect is most likely associated with an increase in the extracellular adenosine offer and signaling through adenosine A2A receptor.[12] Another 2012 study found similar anti-inflammatory effects from an even smaller dose of CBD when treating acute pancreatitis in mice.[13] These conclusions support the findings of earlier studies like a 2006 investigation of CBD that found it could be used effectively as an oral therapeutic agent for chronic inflammatory and neuropathic pain.[14]

  10. Adverse effects says:

    CBD safety in humans has been studied in multiple small studies, suggesting that it is well tolerated at doses of up to 1,500 mg/day given orally or 30 mg given intravenously.[25] Daily doses of CBD (700 mg) for 6 weeks did not induce any toxicity in patients being treated for Huntington’s disease.[26]

  11. Chemistry says:

    Cannabidiol is insoluble in water but soluble in organic solvents such as pentane. At room temperature, it is a colorless crystalline solid.[44] In strongly basic media and the presence of air, it is oxidized to a quinone.[45] Under acidic conditions it cyclizes to THC.[46] The synthesis of cannabidiol has been accomplished by several research groups.[47][48][49]


  12. Pharmaceutical drug says:

    Medicine is the science and practice of the diagnosis, treatment, and prevention of disease. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.[1]

    Medicine has existed for thousands of years, during most of which it was an art (an area of skill and knowledge) frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). While stitching technique for sutures is an art learned through practice, the knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

  13. Effects of CBD Oil (Cannabidiol) says:

    Cannabidiol (CBD) is emerging as a powerful supplement with anti-inflammatory properties and the ability to help several previously untreatable diseases. CBD Oil can help fight cancer and irritable bowel diseases, improve schizophrenia symptoms, and even relieve anxiety and help you get more sleep. Read this post to learn about cutting-edge findings on the health benefits of CBD and how to best use CBD Oil to improve your life.

    I’ve personally treated over 1,000 clients suffering from things like brain fog and headaches all the way to chronic autoimmune disorders and infections and CBD Oil is one of the most beneficial substances I’ve found that has helped people across a spectrum of different illnesses.

    If you’d like to learn more, I get more in-depth about Cannabidiol as well as all the other biohacks I’ve used to turn people’s lives around in SelfHacked Secrets. It’s a great place to start your journey if you want to learn the basics of biohacking or a great place to end your journey if you’re ready to finally be done with chronic illnesses and get your life back.

  14. CBD Fights Against Cancer says:

    CBD and other chemicals found in Cannabis have an antitumor effect and could be used to improve standard treatments (R).

    CBD successfully stopped cancer cells in multiple different cervical cancer cells (R, R2).

    CBD increased tumor cell death in leukemia and colon cancer (R, R2, R3).

    It also decreased human glioma cell growth and invasion, thus suggesting a possible role of CBD as an antitumor agent (R, R2).

    Cannabinoids may be promising tools in combination therapy for breast and prostate cancer, due to their direct antitumor effects, their ability to improve the effectiveness of conventional antitumor drugs, and their usefulness as a treatment to reduce pain (R, R2, R3).

    Anticancer Mechanisms:

    CBD decreased the ability of the cancer cells to produce energy, leading to their death (R).
    CBD treatment helps lymphokine-activated killer (LAK) cells kill cancer cells better (R).
    CBD blocks CPR55 signaling, decreasing cancer cell proliferation.

  15. CBD Reduces Inflammation and Autoimmunity says:

    Due to its anti-inflammatory role, CBD is a very promising therapeutic agent for a variety of inflammatory and pain-associated disorders.

    If you’re looking to learn more about reducing inflammation, stress, and more from your life, check out our Free 6 part eCourse to get you started biohacking your way to better health.

  16. CBD Can Blunt Th1 and Th2 Dominance says:

    In a rat model of asthma, both Th1 (IL-6 and TNF-a) and Th2 (IL-4, IL-5, IL-13) responses are reduced by CBD treatment (R).

    CBD decreased the production and release of inflammatory cytokines such as Th1 (TNF-alpha, IFN-gamma, and IL-6), Th2 (IL-4), and IL-8 (R, R2).

    Learn more about Th1/Th2/Th17 Dominance including the best ways to work with your specific dominance to achieve a healthier you in SelfHacked Secrets.

  17. CBD May Protect From Neurodegenerative Diseases says:

    CBD was found to prevent toxic effects of neurotransmitter glutamate and radical oxygen species (ROS) in the brain, thus preventing brain cell death (R, R2).

    CBD has antioxidant activity greater than vitamin C (ascorbic acid) or vitamin E (α-tocopherol) (R).

    CBD may also protect brain cells from beta-amyloid toxicity, making it a potential therapy in Alzheimer’s and Parkinson’s disease (R, R2).

    CBD may also protect the brain in cases where blood flow is reduced (ischemia) (R, R2).

    Early human studies showed a dose-related improvement in patients with Parkinson’s disease treated with 100–600 mg/day of CBD over a 6-week period (R).

    However, another study failed to show any beneficial effect of a mixture of THC and CBD either on Parkinson’s disease or dyskinesia (R).

    CBD has been shown to reverse cognitive deficits of Alzheimer’s disease in animal models (R).

    CBD, due to its anti-inflammatory and antioxidant properties, may be a promising agent to treat and prolong survival in Amyotrophic Lateral Sclerosis (ALS) patients (R).

  18. CBD May Relieve Multiple Sclerosis Symptoms says:

    Cannabis derivatives may relieve symptoms in multiple sclerosis patients (R).

    A combination of CBD and THC is effective and well tolerated in the treatment of muscle tightness, pain, sleep disturbances, and loss of bladder control (urinary incontinence) in people with multiple sclerosis (R, R2, R3).

  19. CBD Has Therapeutic Potential for Schizophrenia says:

    CBD is a potential treatment for psychosis (R, R2).

    CBD improves the symptoms of schizophrenia, but the mechanism of action is unknown (R, R2).

    Studies suggest that CBD has similar effects as atypical antipsychotic drugs, but with fewer side effects (R).

  20. CBD Helps with Epileptic Seizures says:

    CBD may be a promising therapy for treatment-resistant epilepsy (R, R2).

    In a survey including parents of children with treatment-resistant epilepsy, 84% of parents reported a reduction in their child’s seizure frequency while taking CBD (R).

    These children also experienced increased alertness, better mood, and improved sleep. Drowsiness and fatigue occurred as side effects (R).

    After 3 months of treatment with a purified 98% oil-based CBD extract, 39% of children with treatment-resistant epilepsy had a more than a 50% reduction in seizures (R).

    7 out of 8 patients suffering from secondary generalized epilepsy and resistant to antiepileptic drugs had improvement of their disease state after receiving 200-300 mg/d of cannabidiol for up to 4.5 months (R).

  21. CBD Reduces Anxiety says:

    Cannabidiol reduces anxiety in both healthy individuals and patients with social anxiety disorder (R, R2).

    Studies showed that CBD significantly reduced anxiety and discomfort caused by public speaking (R, R2).

    CBD also reduced anxiety caused by the use of THC (R).

    Researchers suggest that it may be effective for panic disorder, obsessive-compulsive disorder and post-traumatic stress disorder (R).

    CBD is a potential therapy for posttraumatic stress disorder (PTSD) treatment (R).

    Want to learn more about reducing stress, anxiety, chronic inflammation, and getting better sleep? Check out our free 6 part eCourse to begin your biohacking journey.

  22. CBD Relieves Pain says:

    Studies suggest that cannabinoids may be a new class of drugs for the treatment of chronic pain (R, R2).

    CBD significantly decreased chronic inflammatory and neuropathic pain in rodents (R).

    Cannabidiol, especially in a combination with THC, shows promising results for the treatment of postoperative pain, chronic pain associated with multiple sclerosis, cancer, rheumatoid arthritis, and neuropathic pain (R, R2, R3).

    Sativex, a combination of CBD and THC as a sublingual spray, is effective in treating neuropathic pain in patients with multiple sclerosis and in cancer patients with advanced pain (R, R2).

    Studies have shown that CBD and opioids act together to relieve pain (R).

  23. CBD May Be Beneficial in Rheumatoid Arthritis says:

    Due to its anti-inflammatory effect, cannabinoids may provide relief of joint pain and swelling and decrease joint destruction and disease progression (R).

    Administration of CBD protected joints against severe damage, decreased progression, and produced improvement of arthritis in animal models (R).

    The first controlled trial showed that administration of Sativex over five weeks produced significant improvements in the intensity of pain on movement and at rest, quality of sleep, and inflammation. No serious adverse effects were observed (R).

  24. Cannabidiol Relieves Nausea and Increases Appetite says:

    A study showed that CBD relieved nausea and vomiting when it was given to rats (R).

    Researchers found that CBD in low doses decreases nausea and vomiting produced by toxic drugs, but in high doses it increases nausea or has no effect in animal models (R, R2).

    THC is an approved drug used to treat nausea and vomiting (dronabinol) in human patients, but more clinical studies proving the efficacy of CBD are needed in humans (R).

    According to the National Cancer Institute, CBD increases appetite by binding to cannabinoid receptors in the body (R).

    CBD Oil helped me greatly reduce my food sensitivities. If you struggle with food sensitivities, I’d recommend experimenting with CBD oil as well as the Lectin Avoidance Diet, a diet specifically designed to help you pinpoint the exact foods that give you a reaction so you can start eating worry free.

  25. Cannabidiol Lowers Incidence of Diabetes says:

    The study which included 4,657 adult men and women showed that current marijuana use was associated with 16% lower fasting insulin levels, and smaller waist circumferences, a factor connected to the onset of diabetes (R).

    Cannabidiol significantly reduces the development of diabetes in young non-obese mice, from 86% in non-treated mice to only 30% in mice treated with CBD (R, R2).

    Cannabidiol can inhibit and delay the destruction of insulin-producing pancreatic cells and the production of inflammatory cytokines in diabetics (R).

    This data strengthens assumptions that CBD, which is known to be safe in humans, can possibly be used as a therapeutic agent for treatment of type 1 diabetes at an early stage of the disease (R).

  26. Cannabidiol May Promote Heart Health says:

    A study reported that CBD caused dilation of arteries and protected blood vessel from damage in animal models (R).

    CBD reduced the infarct size (size of damage from clogged blood vessels) in the heart and brain and irregular heart rhythms in animal models (R, R2).

    Studies showed that CBD reduced the heart rate and blood pressure in response to anxiety or stressful situations (R, R2).

    CBD also influenced white blood cell function and platelet aggregation (R, R2).

    However, further work is required to prove the ability of CBD to prevent the development of heart and blood vessels disorders in humans.


    Overall, CBD affects the body through its interaction with the body’s endocannabinoid system. Found in all mammals, the endocannabinoid system is tasked with regulating a wide variety of bodily functions – such as mood, appetite, sleep, hormone production, and even nervous and immune system responses. The endocannabinoid system is regularly modulating these functions in an effort to keep the body in homeostasis, helping users to feel and function at their best.

    Products made with CBD are safe to use by all members of your family. CBD is non-toxic and non-psychoactive, even at high levels, and carries no significant side effects. Learn more about CBD’s safety HERE.


    Thousands of studies have demonstrated the wide array of potential benefits that cannabidiol may have, and clinical trials for CBD-based pharmaceutical drugs are underway for a range of medical conditions.

    CBD has already become a mainstream ingredient in all kinds of common products. Any controversy over this beneficial, non-psychoactive cannabinoid is quickly dissipating, as lawmakers, officials, and consumers in the U.S. and internationally begin to recognize CBD’s potential.

    Countries like Mexico, Brazil, and Paraguay have already approved the use of CBD as a prescription medication, and dozens of other countries around the world allow the use of CBD as a dietary supplement. Late in 2017, the World Health Organization officials announced their recommendation that CBD should not be scheduled as a drug. This decision could affect policies regarding CBD in countries worldwide – including the U.S.


    CBD hemp oil products are available for purchase in many retail locations across the U.S. and from Medical Marijuana, Inc.’s online shop. When shopping for CBD products, be sure to purchase from a source you trust. Ask these 5 questions about your hemp oil source before buying.

    You can learn more about CBD and its benefits on our CBD Oil Education page, or shop our online store today to get started adding CBD to your system

  30. What is cannabidiol (CBD)? says:

    Cannabidiol (CBD) is one of the most prevalent chemical compounds in the cannabis plant. Unlike the more famous molecule, tetrahydrocannabinol (THC), CBD is completely nonpsychoactive.

    Don’t expect to get “high” off of this organic chemical, however. CBD is all relaxation without intoxication.

    While CBD still has an effect on your body, consuming CBD by itself isn’t going to send you on the cerebral adventure associated with THC. For decades, medical professionals and the general public overlooked CBD because psychoactive cannabis took center stage.

    Now, the medical potential of CBD has taken cannabis to mainstream audiences. Preclinical trials over the past four decades have found that the cannabinoid shows promise as an:

    anti-tumoral agent
    CBD is often used by patients in the form of an oil. Patients with more chronic conditions such as cancer and epilepsy often use medical cannabis oil extracted from high-CBD varieties of cannabis

  31. What is CBD used to treat? says:

    The therapeutic value of CBD is almost unbelievable. For decades, outdated laws have banned a plant that produces what may become one of the most important medicines for modern disease.

    CBD is polypharmacological, meaning that it can affect multiple different pathways in the body at once. This makes it extremely difficult to study, as it is almost impossible to tell what effect these different interactions have upon each other. However, regardless of a lack of high-quality human trials, many medical cannabis patients find relief with this calming cannabinoid. Here are a few of the common reasons patients use CBD:

    Motor disorders
    Nicotine addiction
    Parkinson’s Disease
    Chronic and neuropathic pain
    Obsessive Compulsive Disorder
    Various pediatric conditions

  32. A Primer About Cannabidiol And The Benefits Of CBD says:

    Many of cannabinoids have therapeutic value and CBD is no exception.
    Scientists are rapidly discovering more and more about the rather amazing abilities of the cannabinoids found in the cannabis plant. Most of them have shown therapeutic value, as have the terpenes, which give the plant its distinct odors. There are over 125 terpenes and over 80 cannabinoids in cannabis and each strain has its own unique blend that create its distinct effects.

    CBD is just one cannabinoid. Cannabinoids are 21-carbon molecules that block or stimulate endocannabinoid receptors. It’s known that other cannabinoids, such as THC, THCV, CBN and CBD, bind to CB1 and/or CB2 receptors, just as do the brain’s own naturally occurring cannabinoids – AEA and 2 AG.

    Many of these cannabinoids have therapeutic value and CBD is no exception. It is a non-psychotropic cannabinoid, meaning it does not contribute to the euphoria associated with certain strains of cannabis. It is, however, psychoactive, because it crosses the blood-brain barrier. Unlike THC, CBD can be administered at relatively high doses without undesired psychological side eff

  33. The big selling point for the surging popularity of CBD has been that it is non-euphoric. says:

    CBD also has the effect of reducing the undesirable effects of high-THC cannabis, such as anxiety and paranoia, which allows a patient to ingest more THC, which has its own incredible medical effects. CBD is a powerful anti-epileptic, anti-depressant, anti-inflammatory, anti-nauseate, sleep aid, muscle relaxant, sedative and anti-proliferative.

  34. Entourage Effect says:

    Many clinicians believe that using CBD as an isolated compound not only diminishes its therapeutic value but does not take full advantage of the medicinal value of cannabis. This is because of the entourage effect, the concept that the totality of the therapeutic constituents of the plant acting together are more effective than any single isolated compound acting alone.

    The federal government promotes the concept that “Single-molecule pharmaceuticals are superior to ‘crude’ whole plant medicinals.” Here’s what Martin Lee, author of ‘Smoke Signals’ and ‘Acid Dreams’ had to say about this issue:

    “According to the federal government, specific components of the marijuana plant (THC, CBD) have medical value, but the plant itself does not have medical value. Uncle Sam’s single-molecule blinders reflect a cultural and political bias that privileges Big Pharma products. Single-molecule medicine is the predominant corporate way, the FDA-approved way, but it’s not the only way, and it’s not necessarily the optimal way to benefit from cannabis therapeutics. Cannabis contains several hundred compounds, including various flavonoids, aromatic terpenes, and many minor cannabinoids in addition to THC and CBD. Each of these compounds has specific healing attributes, but when combined they create what scientists refer to as a holistic “entourage effect,” so that the therapeutic impact of the whole plant is greater than the sum of its single-molecule parts. The Food and Drug administration, however, isn’t in the business of approving plants as medicine. [See the scientific evidence].”

  35. Earlier this year Brazil approved the use of CBD to treat epilepsy. Prescribing is restricted to psychiatrists and neurologists. says:

    Mechoulam has characterized post-traumatic stress disorder, certain phobias and forms of chronic pain as human situations which are conditioned and might be amenable to treatment with CBD.

    “I know that many patients with PTSD take cannabis, self-administered,” Mechoulam said.

    The Israeli Ministry of Health has tested CBD and THC at various ratios to treat PTSD. They currently have a successful program at Abarbanal Hospital in Israel where cannabis is used to treat PTSD.

  36. Cannabinoids, Tumors and Cancer says:

    Cannabis has been shown in both tissue culture and mice to be effective at inhibiting the growth of many cancers. CBD plays an important role in that effort. Other cannabinoids also contribute to cannabis’ anti-neoplastic (anti-cancer) effect. Cannabis is an anti-oxidant. Antioxidants have been shown to decrease the incidence of cancer. There are several mechanisms for this anti-cancer effect: cannabis affects a gene which controls metastasis so it decreases metastasis, encourages apoptosis (death of old or abnormal cells), and inhibits angiogenesis (formation of new blood vessels).

    In 1974, a research team at the Medical College of Virginia (acting at the behest of the federal government) discovered that cannabis inhibited malignant tumor cell growth in cell culture and in mice. This is the study that was published in the above referenced Journal of the National Cancer Institute in 1975, According to the study’s results, reported nationally in an August 18, 1974 Washing Post newspaper feature, administration of marijuana’s primary cannabinoid THC, “slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.”

  37. Can hemp extract provide health benefits without getting you high? says:

    Is there a substance that gives us the health benefits of marijuana without getting us stoned?

    Some people think the answer lies in cannabidiol, or CBD. Like the more well-known tetrahydrocannabinol (THC), this molecule is very abundant in cannabis; in some cases, CBD is the most or second-most abundant molecule. And they both come from the same plant, though CBD is mostly found in a different strain, called hemp.

    But compared to THC, cannabidiol doesn’t create psychoactive results — and that’s why you see people selling CBD oil you can take by mouth to relieve chronic pain, inflammation, or anxiety. Though you can easily buy it on the internet, CBD falls under the same laws as marijuana, meaning that it’s illegal at the federal level. But it’s not clear whether you’re getting your money’s worth.

    First things first: CBD oil definitely won’t have the same effects as smoking marijuana. The active psychoactive ingredient in marijuana, THC, binds very well to the cannabinoid 1 receptor in the central nervous system, says Norbert Kaminski, a toxicologist at Michigan State University who studies the effects of cannabinoids on the immune system. (Researchers only figured out the shape of this receptor last year, and the way that THC binds is responsible for a lot of the subjective effects of getting high.)

    CBD simply doesn’t bind the same way and it’s generally not associated with the psychotropic effects produced by THC, adds Kaminski. According to Sachin Patel, a Vanderbilt University professor who studies cannabis, there have been some clinical trials in which participants have been exposed to relatively large doses of CBD without negative effects.

    So CBD is safe, and it won’t make you high. But should you shell out for the oil?

    Truth is, it’s unknown what its real effects are because there’s not enough research, says Patel. Most of the CBD studies going on right now are focus on cases such as childhood epilepsy that haven’t responded to traditional treatment, or schizophrenia and anxiety. Some rodent studies suggest that CBD might interact with the chemical serotonin, he added. Anti-depressants work with serotonin as well, so perhaps CBD might also interact with serotonin to be effective at reducing anxiety.

    Ultimately, says Kaminski, “there’s really a great need for more cannabis studies conducted in people.” These types of studies have been very difficult because historically there has not been much support or funding for research looking at the therapeutic effects of cannabinoids, as opposed to the dangers.

    In the meanwhile, the good news is that that even if that hemp oil won’t make your anxiety any better, at least it can’t hurt.

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